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This article is an orphan, as few or no other articles link to it. Please introduce links to this page from related articles; suggestions are available. (February 2009) edit Cleavage and polyadenylation specific factor 3-like Identifiers Symbols CPSF3L; CPSF73L; FLJ13294; FLJ20542; INT11; INTS11; RC-68; RC68 External IDs MGI: 1919207 HomoloGene: 9894 GeneCards: CPSF3L Gene Gene Ontology Molecular function • protein binding • hydrolase activity Cellular component • nucleus • integrator complex Biological process • snRNA processing Sources: Amigo / EGO RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 54973 71957 Ensembl ENSG00000127054 ENSMUSG00000029034 UniProt Q5TA45 Q9CWS4 RefSeq (mRNA) NM_032179 NM_028020 RefSeq (protein) NP_115555 NP_082296 Location (UCSC) Chr 1: 1.24 - 1.25 Mb Chr 4: 154.71 - 154.73 Mb PubMed search [1] [2] Integrator complex subunit 11 is a protein that in humans is encoded by the CPSF3L gene.[1][2][3] References ^ Dominski Z, Yang XC, Purdy M, Wagner EJ, Marzluff WF (Feb 2005). "A CPSF-73 homologue is required for cell cycle progression but not cell growth and interacts with a protein having features of CPSF-100". Mol Cell Biol 25 (4): 1489–500. doi:10.1128/MCB.25.4.1489-1500.2005. PMID 15684398.  ^ Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N, Shiekhattar R (Oct 2005). "Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II". Cell 123 (2): 265–76. doi:10.1016/j.cell.2005.08.019. PMID 16239144.  ^ "Entrez Gene: CPSF3L cleavage and polyadenylation specific factor 3-like". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=54973.  Further reading Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMID 11076863.  Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422–35. doi:10.1101/gr.154701. PMID 11230166.  Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336.  Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.  Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901.  Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.  This article on a gene on chromosome 1 is a stub. You can help Wikipedia by expanding it. v • d • e